Fe3O4-PAA–(HP-γ-CDs) Biocompatible Ferrimagnetic Nanoparticles for Increasing the Efficacy in Superparamagnetic Hyperthermia

ABD

Industry: Nanomedicine
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Instrument: Vasco, Wallis

Industry: Nanomedicine

DOI: https://doi.org/10.3390/nano12152577

Keywords: Fe3O4-PAA nanoparticles; HP-γ-cyclodextrins; nanobioconjugates; superparamagnetic hyperthermia; human HaCaT cells; cell viability; MTT assay

In this paper, we present the obtaining of Fe3O4-PAA–(HP-γ-CDs) ferrimagnetic nanobioconjugates (PAA: polyacrylic acid, HP-γ-CDs: hydroxypropyl gamma-cyclodextrins) in a hybrid core-shell biostructure (core: inorganic Fe3O4 nanoparticles, and shell: organic PAA–(HP-γ-CDs)) and their use in superparamagnetic hyperthermia without cellular toxicity and with increased efficacy for future alternative cancer therapy. (367 characters)

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