The study aims to develop a layer-by-layer (LbL) self-assembled coating of Kappa carrageenan (KC) and heparin-loaded chitosan nanoparticles on the AZ91 alloy modified using micro-arc oxidation (MAO) to control its high corrosion rate and improve the hemocompatibility. In this regard, after the MAO process, polyethylene imine (PEI) coating was initially coated on the AZ91 samples. (328 characters)