In the present study, polyurethane (PU) nanocomposite scaffolds containing bioactive glass nanoparticles (BG-NPs) were successfully fabricated through the electrospinning process. The BG-NPs were synthesized through the sol–gel method. PU solutions (10% w/v) containing different weight percentages of the BG-NPs (5, 10 and 15 wt.%) in dimethylformamide/tetrahydrofuran were prepared. (339 characters)