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Spontaneous Self-Assembly of Polymeric Nanoparticles in Aqueous Media: New Insights From Microfluidics, In Situ Size Measurements, and Individual Particle Tracking

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Industry: Nanomedicine
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Instrument: Vasco Flex

Industry: Nanomedicine

DOI: https://doi.org/10.1016/j.xphs.2016.09.024

Keywords: cyclodextrins, nanoparticles, particle size, distribution, self-assembly, In Situ Dynamic Light Scattering

Supramolecular cyclodextrin-based nanoparticles (CD-NPs) mediated by host-guest interactions have gained increased popularity because of their “green” and simple preparation procedure, as well as their versatility in terms of inclusion of active molecules. Herein, we showed that original CD-NPs of around 100 nm are spontaneously formed in water, by mixing 2 aqueous solutions of (1) a CD polymer and (2) dextran grafted with benzophenone moieties. (386)

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With a single and continuous measurement, VASCO KIN™ gives you access to all characterization data of your reaction (size distribution evolution over time).