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Assessment of microRNA-21 using gold nanoparticle-DNA conjugates based on colorimetric and fluorescent detection

The miR-21 detection is essential for the accurate and early diagnosis or prognosis of most diseases. In the current study, the miR-21 detection method was performed based on the exploitation of the simple colorimetric biosensor due to the unique surface…

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Assessment of 177Lu-labeled carboxyl-terminated polyamidoamine (PAMAM) dendrimer-RGD peptide conjugate

Structurally unique polyamidoamine (PAMAM) dendrimers implanted with targeting biological moiety along with complexed radiometal constitute a favorable nano-system for diagnosis and therapy of targeted tumor sites. In the present study, carboxyl functionalities of PAMAM- generation 4 dendrimer (PAMAM-G4-COOH) were conjugated…

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AS1411 aptamer conjugated gold nanoclusters as a targeted radiosensitizer for megavoltage radiation therapy of 4T1 breast cancer cells

In the present study, AS1411 aptamer conjugated gold nanoclusters (GNCs) have been introduced as a targeted radiosensitizer for enhancing megavoltage radiation therapy efficacy. GNCs with an ultra-small gold core and a bovine serum albumin shell (BSA) as a versatile nano-platform…

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Are nanoplastics able to bind significant amount of metals? The lead example

The nanoscale size of plastic debris makes them potential efficient vectors of many pollutants and more especially of metals. In order to evaluate this ability, nanoplastics were produced from microplastics collected on a beach exposed to the North Atlantic Gyre.…

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Application of TOPSIS algorithm in describing bacterial cellulose-based composite hydrogel performance in incorporating methylene blue as a model drug

A multi-component hydrogel was developed using bacterial cellulose, alginate, and gelatin with the aid of glycerol as trihydric alcohol which participates in re-distribution of hydrogen bonds in the test system. FTIR, XRD, SEM, and TGA as instrumental techniques were used…

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